| Grant Gustin | Barry Allen / The Flash |
| Candice Patton | Iris West-Allen |
| Danielle Panabaker | Caitlin Snow / Killer Frost / Frost |
| Danielle Nicolet | Cecile Horton |
| Kayla Compton | Allegra Garcia |
| Brandon McKnight | Chester P. Runk |
| Jon Cor | Mark Blaine / Chillblaine |
| Hartley Sawyer | Ralph Dibny / Elongated Man |
| Devon Graye | Axel Walker / The Trickster |
| Corinne Bohrer | Zoey Clark / Prank |
| Bill Goldberg | Big Sir / David P. Rachet |
| Richard Brooks | Warden Gregory Wolfe |
| Fraser Aitcheson | Prison Gang-Goon #1 |
| Reese Alexander | Prison Guard #2 |
| Chad Bellamy | Prison Gang-Goon #2 |
| Corina Bizim | Pizza Delivery Woman |
| Ben Diskin | Beebo (voice) |
| Michael Kiapway | Prison Guard #1 |
| Sean Millington | Prison Gang Leader |
| Dana Stoutenburg | Naomi Norris |
| Andrew Robert Wilson | Chinese Food Delivery Man |
| Eduard Witzke | Robber |
| Jessica Parker Kennedy | Mystery Girl |